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Synthesis and characterization of defensin NP-1

โœ Scribed by RAO, A. GURU RAJ ;ROOD, TRACY ;MADDOX, JOYCE ;DUVICK, JONATHAN

Book ID
115099348
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
884 KB
Volume
40
Category
Article
ISSN
0367-8377

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Chemical synthesis, characterization and
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โœ Nicola F. Dawson; David J. Craik; Ailsa M. Mcmanus; Stuart G. Dashper; Eric C. R ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 141 KB

The 32-residue peptide, RK-1, a novel kidney-derived three disulfide-bonded member of the antimicrobial h-defensin family, was synthesized by the continuous flow Fmoc-solid phase method. The crude, cleaved and S-reduced linear peptide was both efficiently folded and oxidized in an acidic solution of