Synthesis and Characterization of Covalently Linked Single-Stranded DNA Oligonucleotide−Dendron Conjugates
✍ Scribed by Bell, Stephen A.; McLean, Megan E.; Oh, Sang-Keun; Tichy, Shane E.; Zhang, Wen; Corn, Robert M.; Crooks, Richard M.; Simanek, Eric E.
- Book ID
- 125921995
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 165 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1043-1802
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## Abstract ## Background Single‐stranded oligonucleotides (ssODN) can induce site‐specific genetic alterations in selected mammalian cells, but the involved mechanisms are not known. ## Methods We corroborate the potential of genomic sequence correction by ssODN using chromosomally integrated m
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