𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and Characterization of Chitosan Grafted Oligo(L-lactic acid)

✍ Scribed by Fanglian Yao; Chang Liu; Wei Chen; Yun Bai; Zhiyuan Tang; Kangde Yao

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
77 KB
Volume
3
Category
Article
ISSN
1616-5187

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Chitosan grafted oligo(L‐lactic acid) copolymers with different length of side chain were prepared through the reaction of terminal aldehyde group of oligo(L‐lactic acid) (OLLA) and amino groups of chitosan. The mean molecular mass of the grafting OLLA chain was ca. 600 ∼ 5 000. The graft copolymers are soluble in DMSO, DMF and acetic acid. The synthesis method and structure described here provide chitosan‐g‐OLLA copolymers with broad applicability.

Structure of chitosan‐g‐oligo(L‐lactic acid).

magnified imageStructure of chitosan‐g‐oligo(L‐lactic acid).

📜 SIMILAR VOLUMES

Synthesis and characterization of pH-sen
Synthesis and characterization of pH-sensitive hydrogels based on chitosan and D,L-lactic acid
✍ Xin Qu; Anders Wirsén; Ann-Christine Albertsson 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 270 KB 👁 2 views

Novel pH-sensitive physically crosslinked hydrogels were synthesized by grafting D,L-lactic acid (LA) onto the amino groups in chitosan (CS) without a catalyst. The structures of these graft copolymers were analyzed by FTIR and X-ray measurements. Degree of substitution, side-chain length, and yield

Synthesis and characterization of lactob
Synthesis and characterization of lactobionic acid grafted pegylated chitosan and nanoparticle complex application
✍ Wen Jen Lin; Tze Dan Chen; Chia-Wen Liu 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 834 KB

A series of chemical modifications of chitosan were conducted by grafting a hydrophilic methoxy poly(ethylene glycol) (MPEG) and a target sugar molecule lactobionic acid (LA). The MPEG was grafted onto C6-OH position of chitosan, and the grafting degree was reduced for chitosan with high degree of d

Synthesis and Characterization of Carbox
Synthesis and Characterization of Carboxymethyl Chitosan Grafted Methacrylic Acid Initiated by Ceric Ammonium Nitrate
✍ Jigar M. Joshi; Vijay Kumar Sinha 📂 Article 📅 2006 🏛 Springer 🌐 English ⚖ 855 KB

O-carboxymethyl chitosan (CMCH) was prepared and characterized by FTIR spectroscopy and X-ray diffraction. Grafting of methacrylic acid (MA) onto CMCH using ceric ammonium nitrate (CAN) as an initiator was carried out under nitrogen atmosphere in aqueous solution. Evidence of grafting was confirmed

Synthesis and characterization of grafti
Synthesis and characterization of grafting β-cyclodextrin with chitosan
✍ Xueyong Zhang; Yuting Wang; Ying Yi 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 101 KB 👁 1 views

## Abstract Two new adsorbents [β‐cyclodextrin–chitosan (β‐CD–CTS) and β‐cyclodextrin‐6–chitosan (β‐CD‐6‐CTS)] were synthesized by the reaction of β‐cyclodextrin (β‐CD) with epoxy‐activated chitosan (CTS) and the sulfonation of the C‐6 hydroxyl group of β‐cyclodextrin with CTS, respectively. Their

Preparation and characterization of poly
Preparation and characterization of poly(L-lactic acid)-chitosan hybrid scaffolds with drug release capability
✍ M. Prabaharan; M. A. Rodriguez-Perez; J. A. de Saja; J. F. Mano 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 498 KB

## Abstract Novel poly(L‐lactic acid) (PLLA)–chitosan hybrid scaffolds were developed in order to be used as tissue‐engineering scaffolds and drug release carriers. The incorporation of chitosan into the PLLA porous structure allows for producing chitosan‐based scaffold devices with interesting dam