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Synthesis and characterization of biodegradable pH-sensitive poly(acrylic acid) hydrogels crosslinked by 2-hydroxyethyl methacrylate modified poly(L-glutamic acid)

✍ Scribed by Xiaoye Gao; Chaoliang He; Chunsheng Xiao; Xiuli Zhuang; Xuesi Chen


Book ID
113795681
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
754 KB
Volume
77
Category
Article
ISSN
0167-577X

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The purpose of this investigation was to define the polymer structure and elucidate the swelling behavior of ionizable hydrophilic polymers (hydrogels) in water and buffered media. Poly(acry1ic acid) (PAA) and poly(acry1ic acid-co-2-hydroxyethyl methacrylate) [P(AA-co-HEMA)] hydrogels were synthesiz