Synthesis and characterization of arsenobetaine and arsenocholine derivatives
β Scribed by R. Minhas; D. S. Forsyth; B. Dawson
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 93 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0268-2605
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β¦ Synopsis
Multigram quantities of arsenobetaine bromide and arsenocholine iodide were synthesized from trimethylarsine using uncomplicated techniques. Arsenobetaine bromide and arsenocholine iodide are both non-hygroscopic. Arsenocholine iodide is, however, light-sensitive and should be used with actinic glassware. Both compounds were characterized by elemental and spectroscopic techniques and found to be suitable for use as primary analytical standards.
π SIMILAR VOLUMES
The titanocene vinylidene intermediate [Cp\* 2 Ti=C=CH 2 ] (9) The azatitanacyclobutane [Cp\* 2 Ti{ΟͺNPhΟͺC(Ph)(H)Οͺ(C= CH 2 )Οͺ}] (22) was formed from the reaction between 9 and reacted with the carbodiimides RΟͺN=C=NΟͺR [R = p-CH 3 C 6 H 4 (19a), C 6 H 11 (19b)] to give the N=C-cycloaddition benzylidene
The reaction of perfluoroaryllithium RC 6 F 4 Li, where R = F trimethylsilyl reagents Me 3 SiX (X = Br, CN, NMe 2 , NEt 2 ) to form 5a, 5b; selenocyanates RC 6 F 4 SeCN (6a, 6b); selenenyl or 4-CF 3 C 6 F 4 O, respectively, with selenium gives the known diselanes (RC 6 F 4 Se) 2 (1a, 1b). Redox reac