Synthesis and Characterization of Amphiphilic Polyethers Based on Tetrahydrofuran and Glycidol: Antibacterial Assessment

✍ Scribed by Stefan Theiler; Thomas Hövetborn; Helmut Keul; Martin Möller

• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 602 KB
• Volume: 210
• Category: Article
• ISSN: 1022-1352
• DOI: 10.1002/macp.200800502

✦ Synopsis

Abstract

Starting from THF and protected glycidols, linear multifunctional polyethers were prepared. Random copolymers were synthesized via cationic ROP while block copolymers were obtained via anionic ROP. Kinetic studies were carried out for the random copolymers. Poly(THF__‐co‐__glycidol) was converted in polymer‐analogous reactions first to phenoxy‐carbonyloxy‐methyl‐substituted polyethers and then to amphiphilic polyethers by conversion of the former substituted polyethers with different functional amines. The resulting amphiphilic polyesters were tested for their bacteriostatic effect.

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