Synthesis and characterization of amphiphilic chlorins for photodynamic tumor therapy (PDT)
β Scribed by Kusch, Dirk ;Meier, Axel ;Montforts, Franz-Peter
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 572 KB
- Volume
- 1995
- Category
- Article
- ISSN
- 0947-3440
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β¦ Synopsis
Abstract
Chlorindicarboxylic acids with different alkyl side chains were prepared and their amphiphilic properties studied. The chemical purity, photophysical properties and the lipophilicity due to the alkyl side chains make the chlorins potential candidates for applications in photodynamic therapy.
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Photodynamic therapy (PDT), or photoradiation therapy (PRT), utilizing hematoporphyrin derivative (HPD) as photosensitizer and an argon-dye laser system as the light source, was used alone and in combination with localized microwave hyperthermia (2450 MHz) to treat axillary tumors of the SMT-F mamma