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Synthesis and Characterization of Adducts Formed in the Reactions of Safrole 2′,3′-Oxide with 2′-Deoxyadenosine, Adenine, and Calf Thymus DNA

✍ Scribed by Li-Ching Shen; Su-Yin Chiang; I-Ting Ho; Kuen-Yuh Wu; Wen-Sheng Chung

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
766 KB
Volume
2012
Category
Article
ISSN
1434-193X

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## Abstract 3‐Nitrobenzanthrone (3‐NBA) is a potent mutagen and potential human carcinogen identified in diesel exhaust and ambient air particulate matter. Previously, we detected the formation of 3‐NBA‐derived DNA adducts in rodent tissues by ^32^P‐postlabeling, all of which are derived from reduc