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Synthesis and characterization of a thermally-responsive tumor necrosis factor antagonist

โœ Scribed by Mohammed F. Shamji; Jun Chen; Allan H. Friedman; William J. Richardson; Ashutosh Chilkoti; Lori A. Setton


Book ID
113691752
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
583 KB
Volume
129
Category
Article
ISSN
0168-3659

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Thermally responsive gels of hydroxypropyl methylcellulose (HPMC) were produced in spherical form by a suspension crosslinking technique. The suspension crosslinking of HPMC with divinylsulfone was accomplished by dispersing aqueous polymer droplets, containing all of the reactants, in a continuous