Synthesis and characterization of a novel lysosomotropic enzyme substrate that fluoresces at intracellular pH

Rational design and synthesis of a novel

Rational design and synthesis of a novel class of highly fluorescent rhodamine dyes that have strong absorption at long wavelengths

✍ Jixiang Liu; Zhenjun Diwu; Wai-Yee Leung; Yixin Lu; Brian Patch; Richard P. Haug 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 215 KB

A novel class of strongly fluorescent rhodamine dyes were designed and synthesized by extending the p conjugation of chromophore with limited flexibility. These dyes were shown to have longer absorption in the range of 581 to 631 nm with quantum yields between 0.64 and 0.89.