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Synthesis and Characterization of a Highly Potent and Selective Isotopically Labeled Retinoic Acid Receptor Ligand, ALRT1550

✍ Scribed by Bennani, Youssef L.; Marron, Kristin S.; Mais, Dale E.; Flatten, Karen; Nadzan, Alex M.; Boehm, Marcus F.


Book ID
126952739
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
170 KB
Volume
63
Category
Article
ISSN
0022-3263

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## Abstract LGD1069, 4‐[1‐(3,5,5,8,8‐pentamethyl‐5,6,7,8‐tetrahydro‐2‐naphthyl)ethenyl] benzoic acid, is the first retinoid X receptor (RXR) selective retinoid to enter clinical trials for treatment of dermatological diseases and cancer. In order to examine biological properties such as receptor bi