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Synthesis and Characterization of a 11C-Labelled Derivative of S12968: An Attempt to Image In Vivo Brain Calcium Channels

✍ Scribed by Frédéric Dollé; Héric Valette; Françoise Hinnen; Chantal Fuseau; Jean-Louis Péglion; Christian Crouzel


Book ID
117688227
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
177 KB
Volume
25
Category
Article
ISSN
0969-8051

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Highly efficient synthesis of [11C]S1296
✍ Frédéric Dolle; Héric Valette; Françoise Hinnen; Stéphane Demphel; Yann Bramoull 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 176 KB

## Abstract The dihydrophyridines S12968 ((−)‐S11568, absolute configuration S) and S12967 ((+)‐S11568, absolute configuration R), 3‐ethyl 5‐methyl (−/+)‐2‐[(2‐(2‐aminoethoxy)ethoxy)methyl]‐4‐(2,3‐dichlorophenyl)‐6‐methyl‐1,4‐dihydropyridine‐3,5‐dicarboxylate, have both an __in vitro__ profile of h