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Synthesis and Characterization of 4′-Bromomethyl-2-( N -trityl-1 H -tetrazol-5-yl) Biphenyl

✍ Scribed by Wang, Guo-xi; Sun, Bao-ping; Ru, Zong-ling


Book ID
127066509
Publisher
Taylor and Francis Group
Year
2008
Tongue
English
Weight
104 KB
Volume
38
Category
Article
ISSN
0039-7911

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## Abstract We recently reported a series of 1‐acyl‐__N__‐(biphenyl‐4‐ylmethyl)pyrrolidine‐2‐carboxamides as AT~1~ receptor ligands. The most potent compound of the series, 1‐pentanoyl‐__N__‐{[2'‐(1__H__‐tetrazol‐5‐yl)biphenyl‐4‐yl]methyl}‐pyrrolidine‐2‐carboxamide, showed an interesting affinity f