𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and characterization of [125I]2-iodo N-[(S)-{(S)-1-methylpiperidin-2-yl}(phenyl)methyl]3-trifluoromethyl-benzamide as novel imaging probe for glycine transporter 1

✍ Scribed by Takeshi Fuchigami; Mamoru Haratake; Yasuhiro Magata; Terushi Haradahira; Morio Nakayama


Book ID
113495467
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
762 KB
Volume
19
Category
Article
ISSN
0968-0896

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Radiosynthesis of [5-[11C]methanesulfony
✍ Emmanuel Pinard; Serge Burner; Philipp Cueni; Thomas Hartung; Roger D. Norcross; πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 French βš– 300 KB

The glycine transporter type 1 (GlyT1) has emerged as a key novel target for the treatment of schizophrenia. We have recently discovered and developed [^11^C]RO5013853 as a novel positron emission tomography tracer for GlyT1 for which a reliable five‐step synthetic route was established. The incorpo

Synthesis and in vivo evaluation of [O-m
✍ Jaya Prabhakaran; Ramin V. Parsey; Vattoly J. Majo; Ronald L. Van Heertum; J. Jo πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 French βš– 224 KB πŸ‘ 1 views

## Abstract 2‐(4‐Methoxyphenyl)‐__N__‐(4‐methylbenzyl)‐__N__‐(1‐methylpiperidin‐4‐yl)acetamide (AC90179, **4**), a highly potent and selective competitive 5‐HT~2A~ antagonist, was labeled by [^11^C]‐methylation of the corresponding desmethyl analogue **5** with [^11^C]methyl triflate. The precursor