Synthesis and characterization of (1 - 13C) Phe9 gramicidin A. Effects of side chain variations
β Scribed by PRASAD, K.U. ;TRAPANE, T.L. ;BUSATH, D. ;SZABO, G. ;URRY, D.W.
- Book ID
- 115097981
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 481 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0367-8377
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This paper presents the synthesis of 1-13 C-and 4-13 C-plastoquinone-9 and their characterization with NMR spectroscopy and mass spectrometry. The synthetic scheme has been further adapted to introduce 13 C-labeled plastoquinones on all individual and on each combination of positions in the qui-
Nitration of I-phenylethyl acetate with NHJ?O,-trijhoroaceiic anhydride gave a mixture of orthoand para-nitro products, which were separable by chromatography ajier saponijication of the acetate. The ortho-isomer [1-(2-nitrophenyl)eihanoll was converted to the 1-(2-nitropheny~ethyl esters of monomet