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Synthesis and Bladder Smooth Muscle Relaxing Properties of Substituted 3-Amino-4-aryl-(and aralkyl-)cyclobut-3-ene-1,2-diones.

โœ Scribed by John A. Butera; Douglas J. Jenkins; Joseph R. Lennox; Jeffrey H. Sheldon; N. Wesley Norton; Dawn Warga; Thomas M. Argentieri


Publisher
John Wiley and Sons
Year
2005
Weight
14 KB
Volume
36
Category
Article
ISSN
0931-7597

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โœฆ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Synthesis and properties of 2-substitute
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Cyclization of 2- (N-acetyl-N-arylamino)nicotinonitriles in the presence of dry HCI gave 1-aryl-2-methyl-4-oxo-l,4-dihydropyrido[2,3-d]pyrimidines. It was shown that they are acylated by acetic anhydride, aroyl chlorides, and phenyl isocyanate at the methyl group and that with benzaldehyde they give