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Synthesis and biotransformation of 2-alkyl-4(1H)-quinolones by recombinantPseudomonas putidaKT2440

✍ Scribed by Heiko Niewerth; Klaus Bergander; Siri Ram Chhabra; Paul Williams; Susanne Fetzner


Publisher
Springer
Year
2011
Tongue
English
Weight
258 KB
Volume
91
Category
Article
ISSN
1432-0614

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Synthesis of 4-hydroxyquinolin-2(1H)-one
✍ Jae-Chul Jung; Young-Jo Jung; Oee-Sook Park πŸ“‚ Article πŸ“… 2001 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 83 KB

## Abstract A versatile synthetic method for preparing 4‐hydroxyquinolone and 2‐substituted quinolone compounds from simple benzoic acid derivatives was demonstrated. The synthetic strategies involve the use of well known ethyl acetoacetate synthesis, malonic ester synthesis and reductive cyclizati