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Synthesis and biological properties of alkyl esters of polyene antibiotics

✍ Scribed by T. Bruzzese; M. Cambieri; F. Recusani

Book ID
102405687
Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
195 KB
Volume
64
Category
Article
ISSN
0022-3549

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✦ Synopsis

Several new alkyl esters of polyene antibiotics were prepared by an improved general procedure, and their toxicity and microbiological activity were tested. Some of these alkyl esters were more active than the nonesterified polyenes against Candida albicans but were less effective than the known methyl esters. Their toxicity was much less than that of the parent compounds.

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