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Synthesis and biological properties of 1,4-substituted thiosemicarbazides and 1,2,4-triazoles

✍ Scribed by A. Kh. Avetisyan; T. R. Ovsepyan; I. A. Dzhagatspanyan; N. E. Akopyan; A. G. Akopyan; L. G. Sapondzhyan; R. V. Paronikyan

Book ID: 112405361
Publisher: Springer
Year: 1978
Tongue: English
Weight: 262 KB
Volume: 12
Category: Article
ISSN: 0091-150X
DOI: 10.1007/bf00772640

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## Abstract Reaction of 4‐phenyl‐4__H__‐1,2,4‐triazole‐3‐thione with ethyl bromoacetate has led to the formation of ethyl [(4‐phenyl‐4__H__‐1,2,4‐triazol‐3‐yl)sulfanyl]acetate **1**, the structure of which was confirmed by X‐ray analysis. In the next reaction with 80% hydrazide hydrate, appropriate