Synthesis and Biological Evaluation of Structural Variants of Carbazoquinocin C.
β Scribed by Alparslan Ayguen; Ulf Pindur
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 93 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
For Abstract see ChemInform Abstract in Full Text.
π SIMILAR VOLUMES
## Abstract A series of analogues of efrapeptinβ C (**1**), with variations in the central tripeptide epitope (positions 6β8), were prepared by a combination of solidβ and solutionβphase peptide syntheses. The conformations of the modified compounds **2**β**6** were investigated by circularβdichrois
Bombesin pseudo-peptide analogues containing a hydroxamide function on the C-terminal part of the molecule, e.g. H-D-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-NHOBzl 1 and H-D-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-NHOH 2 were synthesized. These compounds were tested for their ability to recognize the bombesin recep