𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and biological evaluation of benzoisothiazole derivatives possessing N,N-dimethylformimidamide group as 5-HT6 receptor antagonists

✍ Scribed by Euna Yoo; Faisal Hayat; Hyewhon Rhim; Hea-Young Park Choo


Book ID
113495723
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
287 KB
Volume
20
Category
Article
ISSN
0968-0896

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Synthesis and pharmacological evaluation
✍ Ramakrishna V.S. Nirogi; Anand V. Daulatabad; G. Parandhama; Shaikh Mohammad; K. πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 410 KB

A series of novel aryl aminosulfonamides was designed and synthesized as 5-HT 6 receptor ligands. Many compounds screened in a functional reporter gene based assay displayed potent antagonistic activity with Kb values in the range of 0.02-10 nM. The lead compound 11m exemplified in this series showe