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Synthesis and Biological Evaluation of a New Series of Highly Functionalized 7′- homo -Anhydrovinblastine Derivatives

✍ Scribed by Gherbovet, Olga; Coderch, Claire; García Alvarez, María Concepción; Bignon, Jérôme; Thoret, Sylviane; Martin, Marie-Thèrese; Guéritte, Françoise; Gago, Federico; Roussi, Fanny

Book ID
125474150
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
537 KB
Volume
56
Category
Article
ISSN
0022-2623

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Synthesis of Triazolo[1,5-a]triazin-7-on
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✍ Montserrat Heras; David Font; Anthony Linden; José M. Villalgordo 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 German ⚖ 161 KB

## Abstract The synthesis of novel triazolo[1,5‐__a__]triazin‐7‐ones is presented. Starting from 3‐amino‐5‐sulfanyl‐1,2,4‐triazole, the synthetic sequence involved alkylation with benzyl bromide, reaction with __p__‐nitrophenyl chloroformate followed by treatment with a primary amine, and condensat