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Synthesis and Biological Evaluation of a Multiantigenic Tn/TF-Containing Glycopeptide Mimic of the Tumor-Related MUC1 Glycoprotein

✍ Scribed by Gaëlle-Anne Cremer; Nicole Bureaud; Véronique Piller; Horst Kunz; Friedrich Piller; Agnès F. Delmas

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
214 KB
Volume
1
Category
Article
ISSN
1860-7179

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Dedicated to Professor Steven V. Ley on the occasion of his 60th birthday A common feature of oncogenic transformed cells is the overexpression of oligosaccharides, such as Globo-H, Lewis Y , and Tn antigens. [1][2][3][4] Numerous studies have shown that this abnormal glycosylation can promote metas