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Synthesis and biological evaluation of 5-fluoroquinolone-3-carboxylic acids as potential HIV-1 integrase inhibitors

✍ Scribed by He, Qiu-Qin; Zhang, Xuan; Yang, Liu-Meng; Zheng, Yong-Tang; Chen, Fener


Book ID
120629466
Publisher
Informa plc
Year
2012
Tongue
English
Weight
793 KB
Volume
28
Category
Article
ISSN
1475-6366

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## Abstract Two sets of compounds derived from the fusion of a diversely annulated naphthoxazepinedione system with 1,3‐thiazole and 1,3‐oxazole are described. These compounds are close analogues of previously reported thiazolothiazepine inhibitors of human immunodeficiency virus typeβ€…1 integrase (