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Synthesis and biological evaluation of 3-{[4-(4-[18F]fluorophenyl)methyl] piperazin-1-yl}-methyl-1H-pyrrolo[2,3-b]pyridine for in vivo studies of dopamine D4receptor

✍ Scribed by Hai-Bin Tian; Duan-Zhi Yin; Lan Zhang; Li-Hua Wang; Chun-Fu Zhang; Jun-Ling Li; Wei Zhou; Chun-Ying Wu; Yong-Xian Wang


Book ID
111596436
Publisher
Springer
Year
2004
Tongue
English
Weight
642 KB
Volume
262
Category
Article
ISSN
1588-2780

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## Abstract 3‐[[4hyphen;(4‐[^18^F]fluorophenyl)piperazin‐1‐yl] methyl] ‐1__H__‐pyrrolo[2,3‐b]pyridine, acandidate to image dopamine D~4~ receptors, was synthesised via electrophilic fluorination of a trimethylstannyl precursor with high specific radioactivity [^18^F]F~2~. The precursor was obtained

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