Synthesis and biological activity of spin-labeled analogs of biotin, hexamethonium, decamethonium, dichlorisoproterenol, and propranolol
✍ Scribed by Sinha, Birandra K.; Chignell, Colin F.
- Book ID
- 120824537
- Publisher
- American Chemical Society
- Year
- 1975
- Tongue
- English
- Weight
- 630 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-2623
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📜 SIMILAR VOLUMES
## Abstract Direct introduction of a N‐atom in one step at C (5) of 5‐hydroxyuridine **(4a)** or 5‐hydroxy‐2′‐deoxyuridine **(4b)** by certain primary amines led to the synthesis of two novel C(5)‐N‐spin‐labeled nucleoside analogs and to several C(5)‐N‐aryl adducts. Substitution by 4‐amino‐2,2,6,6‐
## Abstract (N‐t‐Butoxycarbonyl‐S‐acetamido‐methyl‐L‐cysteinyl)‐[1‐ asparagine, 5‐valine]‐angiotensin II (**2**) was prepared from [1‐asparagine, 5‐valine]‥angiotensin II (**1**). With respect to enhancement of rat blood pressure, it is a full agonist displaying about 20–25% of the potency of **1**