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Synthesis and Biological Activity of Some New 1,3,4-Thiadiazole and 1,2,4-Triazole Compounds Containing a Phenylalanine Moiety

✍ Scribed by Moise, Mihaela; Sunel, Valeriu; Profire, Lenuta; Popa, Marcel; Desbrieres, Jacques; Peptu, Cristian

Book ID: 118126872
Publisher: Molecular Diversity Preservation International
Year: 2009
Tongue: English
Weight: 138 KB
Volume: 14
Category: Article
ISSN: 1420-3049
DOI: 10.3390/molecules14072621

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## Abstract magnified image The syntheses of new macrocyclic compounds are described. The 2,5‐bis(hydroxyphenyl)‐1,3,4‐thiadiazole reacts with allyl bromide to give the corresponding allyloxy derivative. The allyl is used to functionalize the ortho position by means of a Claisen rearrangement unde