Fluorinated anthracyclines: Synthesis an
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Ken C. Tonkin; Robert T. C. Brownlee; Franco Zunino; Don R. Phillips
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Article
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1990
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Springer US
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English
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A number of fluorine containing derivatives of daunomycin and Adriamycin have been synthesised with a fluorine substituent located on the C-9 side chain. They included the p-trifluoromethyl-(4) and p-fluorobenzoate (3) esters of Adriamycin and the trifluoro-ethyl-hydrazones of Adriamycin (2) and dau