Synthesis and Biological Activity of Some Benzofuro[3,2-d]pyrimidines.
✍ Scribed by Yadav Bodke; S. S. Sangapure
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 117 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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## Abstract magnified image Carbodiimide, obtained from aza‐Wittig reaction of iminophosphorane with 4‐fluorophenyl isocyanate, reacted with various nucleophiles under mild conditions to give a series of 2‐substituted‐3‐(4‐fluorophenyl)‐benzofuro [3,2‐d] pyrimidin‐4(3H)‐ones in satisfactory yield.
## Abstract magnified image Fifteen novel 3‐substituted‐5‐methyl‐4‐methylene‐7‐alkylsulfanyl‐3,4‐dihydro‐pyrido[4,3‐d]pyrimidine‐8‐carbonitriles **5a**, **5b**, **5c**, **5d**, **5f**, **5g**, **5h**, **5i**, **5j**, **5k**, **5l**, **5m**, **5n**, **5o**, were synthesized __via__ a facile annulat