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Synthesis and biological activity of some 1-alkyl(aryl)-5-methoxy(4,5-dimethoxy)-6-bromoindoles

โœ Scribed by A. N. Grinev; E. K. Panisheva; A. A. Cherkvasova; V. M. Lyubchanskaya; L. S. Sarkisova; A. N. Fomina; I. S. Nikolaeva; E. A. Golovanova


Book ID
111647023
Publisher
Springer
Year
1987
Tongue
English
Weight
334 KB
Volume
21
Category
Article
ISSN
0091-150X

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Synthesis and properties of 1-aryl-2-alk
โœ Liliana R. Orelli; Fernando Niemevz; Marรญa B. Garcรญa; Isabel A. Perillo ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 543 KB

## Abstract A general method is described for the synthesis of 1โ€arylโ€2โ€alkylโ€1,4,5,6โ€tetrahydropyrimidines 1, by cyclization of __N__โ€acylโ€__N__โ€ฒโ€aryltrimethylenediamines 2 with trimethylsilyl polyphosphate. Precursors 2 were obtained by aminolysis of the corresponding __N__โ€(3โ€bromopropyl)amides