Synthesis and biological activity of novel 1,3,5-trisubstituted 1,2,4-triazole derivatives

✍ Scribed by Kokila Parmar; Bharat Suthar; Saraju Prajapati; Arun Suthar

• Publisher: Journal of Heterocyclic Chemistry
• Year: 2010
• Tongue: English
• Weight: 94 KB
• Volume: 47
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.291

✦ Synopsis

Abstract

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Triazole skeleton is ubiquitous in pharmaceutically important compounds. A novel series of indoline‐containing triazole with different amides are described, which exhibit antibacterial and antifungal activities. The chemical synthesis strategies used, the complete characterization of the compounds, their in vitro screening, and the promising activity as reflected in the MIC values are reported. J. Heterocyclic Chem., (2010).