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Synthesis and Biological Activity of Macrocyclic Taxane Analogues.

✍ Scribed by James G. Tarrant; Donald Cook; Craig Fairchild; John F. Kadow; Byron H. Long; William C. Rose; Dolatrai Vyas


Publisher
John Wiley and Sons
Year
2004
Weight
20 KB
Volume
35
Category
Article
ISSN
0931-7597

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The chitinase inhibitor/insect ecdysis inhibitor allosamidin and eight allosamidin analogues have been synthesised from simple carbohydrate starting materials. Allosamidin was assayed against T ineola bisselliella (Hummel) larvae and all nine compounds were examined for their e †ects on the developm