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Synthesis and biological activity of M6-P and M6-P analogs on fibroblast and keratinocyte proliferation

✍ Scribed by Caroline Clavel; Véronique Barragan-Montero; Xavier Garric; Jean-Pierre Molès; Jean-Louis Montero

Book ID
113619862
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
165 KB
Volume
60
Category
Article
ISSN
0014-827X

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Synthesis and Biological Activity of Phosphonate Analogues of Mannose 6-Phosphate (M6P). -Isosteric and non-isosteric analogues (I) and (II) of M6P are synthesized by Wittig-Horner reaction at C-6 of the corresponding sugar aldehyde in case of (I) or, in case of (II), by Michaelis-Arbuzov rearrangem