𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and Biological Activity of Cyclic Peptide Inhibitors of Ribonucleotide Reductase

✍ Scribed by Liehr, Sebastian; Barbosa, Joseph; Smith, Amos B.; Cooperman, Barry S.


Book ID
126130723
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
119 KB
Volume
1
Category
Article
ISSN
1523-7060

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


ChemInform Abstract: Synthesis and Biolo
✍ Sebastian Liehr; Joseph Barbosa; Amos B. Smith III; Barry S. Cooperman πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 26 KB πŸ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

Design, synthesis and evaluation of pept
✍ Johanna Nurbo; Annette K. Roos; Daniel Muthas; Erik WahlstrΓΆm; Daniel J. Ericsso πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 317 KB

## Abstract __Mycobacterium tuberculosis__ ribonucleotide reductase (RNR) is a potential target for new antitubercular drugs. Herein we describe the synthesis and evaluation of peptide inhibitors of RNR derived from the __C__‐terminus of the small subunit of __M. tuberculosis__ RNR. An __N__‐termin

Sequencing cyclic peptide inhibitors of
✍ Shanhua Lin; Sebastian Liehr; Barry S. Cooperman; Robert J. Cotter πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 138 KB

## Abstract Mammalian ribonucleotide reductase (mRR) is a potential target for cancer intervention. A series of lactam‐bridged cyclic peptide inhibitors (1–9) of mRR have been synthesized and tested in previous work. These inhibitors consist of cyclic and linear regions, causing their mass spectral

Synthesis of biologically active cyclic
✍ Nobuo Izumiya; Tetsuo Kato; Michinori Waki πŸ“‚ Article πŸ“… 1981 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 369 KB πŸ‘ 2 views

## Abstract 1. The extent of racemization and the coupling yield in peptide synthesis were studied under high dilution conditions. The azide method yielded the best results. 2. Five linear penta‐peptide precursors related to gramicidin S were subjected to cyclization in order to study how the diffe