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Synthesis and biological activity of 4'-thio analogs of the antibiotic toyocamycin

✍ Scribed by Bobek, M.; Whistler, R. L.; Bloch, A.

Book ID
126922907
Publisher
American Chemical Society
Year
1972
Tongue
English
Weight
565 KB
Volume
15
Category
Article
ISSN
0022-2623

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## Abstract The synthesis of the title compound **1** is described as well as the syntheses of a series of structural analogs of type **4**. The antimicrobial __in vitro__ activity of these vinyl isocyanides, substituted in β‐position either by an indole derivative or by an aryl or 2‐thienyl group,