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Synthesis and biological activity of 2-alkoxybenzimidazoles

โœ Scribed by V. A. Lopyrev; I. A. Titova; E. F. Shibanova; V. N. Kurochkin; A. S. Zaks; L. A. Ovodenko; M. L. Suslina; G. V. Goldobina


Book ID
112400232
Publisher
Springer
Year
1989
Tongue
English
Weight
301 KB
Volume
23
Category
Article
ISSN
0091-150X

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๐Ÿ“œ SIMILAR VOLUMES


Synthesis of N-alkoxybenzimidazoles and
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A variety of novel N-alkoxy aromatic-fused imidazoles have been prepared in a simple two-step process from 2-fluoro nitroaromatics and 2-chloro-3-nitropyridine. The imidazole forming step involves tandem heterocyclisation and O-alkylation with an in situ alkylating agent, and supports prior mechanis

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N-Alkoxy-, N-aryloxy-and N-allyloxybenzimidazoles (prepared using tandem N-alkylation, heterocyclisation and O-alkylation with in situ alkylating agent) can be selectively O-deprotected and then independently realkylated to provide a protocol for diversification with differentiated substituents at C