๐”– Bobbio Scriptorium
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Synthesis and Biological Activities of Hydroxyl-Protected Fluorine-Containing 4,4-Dihydroxylmethyl-2-aryl-iminothiazolidines.

โœ Scribed by Chuanxiang Liu; Xiaoyong Xu; Zhong Li; Weidong Chen; Qingchun Huang; Xuhong Qian


Publisher
John Wiley and Sons
Year
2005
Weight
24 KB
Volume
36
Category
Article
ISSN
0931-7597

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Analogs of Met-enkephalin and [D-Pen 2 , D-Pen 5 ]enkephalin (DPDPE) containing the partially fluorinated amino acid 4,4-difluoro-2-aminobutyric acid (DFAB) in the 2-or 3-position of the peptide sequence were synthesized and their opioid activities and receptor selectivities were determined in vitro