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Synthesis and bioactivity of xyridin A and B, metabolites from xyris indica

✍ Scribed by Dr. Aamer Saeed

Publisher
Journal of Heterocyclic Chemistry
Year
2003
Tongue
English
Weight
34 KB
Volume
40
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

A facile synthesis of the title isocoumarins isolated from. Xyris indica was accomplished. Condensation of butanoyl chloride and 2‐oxo‐butanoyl chloride with 3,4‐methylenedioxyhomophthalic acid afforded xyridin A and xyridin B respectively. Xyridin A was saponified to the corresponding keto acid which on reduction furnished the (±)‐3,4‐dihydro‐6,7‐methylenedioxy‐3‐propylisocoumarin. All of the synthesized compounds were examined in vitro for antibacterial and antifungal activities.

📜 SIMILAR VOLUMES

A Single-Step Synthesis of Xyridins A an
A Single-Step Synthesis of Xyridins A and B, Metabolites from Xyris indica.
✍ Aamer Saeed 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 16 KB 👁 2 views

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