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Synthesis and Bioactivity of Novel N,N′-Diacylhydrazine Derivatives Containing Furan(I)

✍ Scribed by Zi-Ning CUI; Juan HUANG; Ying LI; Yun LING; Xin-Ling YANG; Fu-Heng CHEN

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
99 KB
Volume
26
Category
Article
ISSN
0256-7660

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✦ Synopsis

Abstract

The furan ring system possesses electron‐rich properties and exhibits various biological activities, which was introduced into diacylhydrazine to create novel leading compounds that may serve as improved pesticides and pharmaceuticals. A series of novel diacylhydrazine derivatives containing a furan ring were synthesized by the reaction of 5‐fluorophenyl‐2‐furoyl chloride with substituted benzoylhydrazide in anhydrous dichloromethane under reflux. The structures of the resultant compounds were confirmed by IR, ^1^H NMR, MS and elemental analysis. Insecticidal and anti‐tumor activities of these new compounds were evaluated.

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Synthesis and Bioactivity of Novel N,N′-
Synthesis and Bioactivity of Novel N,N′-Diacylhydrazine Derivatives Containing Furan (III)
✍ Zining Cui; Li Zhang; Juan Huang; Xinling Yang; Yun Ling 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 114 KB

## Abstract 42 novel diacylhydrazine derivatives containing furan were synthesized by the reaction of 5‐substituted phenyl‐2‐furoyl chloride with substituted benzohydrazide in anhydrous dichloromethane under reflux. Their structures were confirmed by IR, ^1^H NMR, MS and elemental analysis. Insecti