✦ LIBER ✦
Synthesis and binding to striatal membranes of no carrier added I-123 labeled 4′-iodococaine.
✍ Scribed by S. A. M. Metwally; S. J. Gatley; A. P. Wolf; D.-W. Yu
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- French
- Weight
- 320 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
An ^123^I labeled cocaine analog, 4′‐[^123^I]iodococaine, has been prepared by oxidative destannylation of the tributyltin analog and shown to interact with cocaine binding sites in rat brain striatal membranes. It may thus be a suitable SPECT radiotracer for studies of the dopamine reuptake site in neurodegenerative diseases.