Synthesis and binding property of an oligonucleotide containing tetrafluorophenoxazine
โ Scribed by Jianying Wang; Kuei-Ying Lin; Mark D. Matteucci
- Book ID
- 108387137
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 167 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In order to evaluate the effect of a new 2%-carbohydrate modification on the hybridization properties of oligonucleotides, uridine 2%-O-carbamates were synthesized and incorporated into DNA strands. The key intermediate in the synthesis, a mixed succinimide carbonate 2, was treated with various amin
The synthesis of 5,6-bicyclic thymine:thymine nucleoside containing a conformationally restricted dioxane acetal has been achieved from 2'-O-allyl 5-methyl uridine. The two diastereomers were separated and incorporated in a single position within an oligonucleotide (ON) sequence. The binding propert