Synthesis and application of poly(ethylene-co-vinylalcohol-graft-acetylsalicylic acid) in drug delivery domain
β Scribed by Nora M. Alotaibi; Siham Lahsasni; Taieb Aouak
- Book ID
- 112002087
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 487 KB
- Volume
- 127
- Category
- Article
- ISSN
- 0021-8995
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Poly(1,4-dioxan-2-one-co-trimethylene carbonate), P(DON-co-TMC), copolymers with different compositions were synthesized by copolymerizations of 1,4dioxan-2-one (DON) and trimethylene carbonate (TMC) at 120ΠC in the presence of Sn(Oct) 2 . Their structures and compositions were determined with FT-IR
## Abstract Starting from D,Lβacid and SnCl~2~ as catalyst, poly(D,Lβlactic acid) (PDLLA) was directly synthesized by melt polycondensation. Under the appropriate conditions such as 0.5 wt % SnCl~2~, 170β180Β°C, 70 Pa, and 10 h, the viscosityβaverage molecular weight (__M__~Ξ·~) of PDLLA was 4100 Da.