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Synthesis and antiviral evaluation of 3′-substituted thymidine analogues derived from 3′-amino-3′-deoxythymidine

✍ Scribed by Christophe Pannecouque; Roger Busson; Jan Balzarini; Paul Claes; Erik De Clercq; Piet Herdewijn


Book ID
103396924
Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
539 KB
Volume
51
Category
Article
ISSN
0040-4020

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✍ El-Barbary, Ahmed A. ;El-Brollosy, Nasser R. ;Abdel-Bary, Hamed M. ;Pedersen, Er 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 539 KB

## Abstract 2,4(1__H__,3__H__)‐Quinazolinediones 3a–c, lumazine (3d) and thieno[2,3‐__d__]pyrimidine‐2,4(1__H__,3__H__)‐dione (8) were silylated and condensed with methyl 2,3‐dideoxy‐3‐fluoro‐5‐__O__‐(4‐phenylbenzoyl)‐β‐D‐__erythro__‐pentofuranoside (2) by using trimethylsilyl triflate as a catalys