## Abstract The reactions of 2‐benzamido‐4,5‐dihydro‐3‐thiophene(‐3‐furan‐)carbonitriles 1a–c (and 11a–c) with acetic (or propionic) anhydride in the presence of tin(IV) chloride give the corresponding 3‐acetyl‐5,6‐dihydro‐2‐phenylthieno(‐furo‐)‐[2,3‐__d__]pyrimidin‐4(3__H__)‐ones 2a–c (and 12a–c)
Synthesis and Antiviral Evaluation of 3-(2,3-Dihydroxypropyl)furo[2,3-d]pyrimidin-2(3H)-ones
✍ Scribed by Zlatko Janeba; Antonín Holý; Robert Snoeck; Graciela Andrei; Erik De Clercq; Jan Balzarini
- Book ID
- 113458333
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 80 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0166-3542
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Synthesis of Functionalized 2,3-Dihydrothieno[2,3-d ]pyrimidin-4(1H )ones and Their Recyclization to 2,3-Dihydrothieno[3,4-d ]pyrimidin-4(1H )-ones
## Abstract The reaction of methyl anthranilate with 4,5‐dichloro‐1,2,3‐dithiazolium chloride (Appel's salt) in the presence of pyridine (2 equivalents) in dichloromethane at room temperature gave methyl __N__‐(4‐chloro‐5__H__‐1,2,3‐dithiazol‐5‐ylidene)anthranilate (3a) (50% yield), which reacted w