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Synthesis and Antiviral Activity of Novel 4′-Branched Carbocyclic C-Nucleoside.

✍ Scribed by Ying Lan Jin; Joon Hee Hong


Publisher
John Wiley and Sons
Year
2006
Weight
27 KB
Volume
37
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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Synthesis and Antiviral Evaluation of No
✍ Jin Woo Kim; Joon Hee Hong 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 108 KB 👁 1 views

## Abstract In this study, we synthesized novel 4′‐hydroxymethyl branched thioapiosyl nucleosides. The thioapiosyl sugar moiety was constructed using sequential ozonolysis and reduction. The natural bases (uracil, thymine, cytosine, and adenine) were efficiently coupled using the Vorbrüggen glycosy