Synthesis and antitumor evaluation of some 1,3,4-oxadiazole-2(3H)-thione and 1,2,4-triazole-5(1H)-thione derivatives
โ Scribed by ChengTao Feng; LingDong Wang; YuGang Yan; Jian Liu; ShaoHua Li
- Publisher
- Springer-Verlag
- Year
- 2010
- Tongue
- English
- Weight
- 333 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1054-2523
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๐ SIMILAR VOLUMES
In the title compound, C 11 H 9 N 5 OS, the molecules are linked into chains along the c axis via N-Hร ร รN hydrogen bonds. The packing is further stabilized by C-Hร ร ร andinteractions.
The title compound, C 15 H 13 N 3 S, was prepared by the reaction of 1-(2-chloroethyl)benzene with hydrazine and phenyl isothiocyanate. Packing is stabilized by N-Hร ร รS intermolecular hydrogen bonds and C-Hร ร ร interactions.
In the molecule of the title compound, C 5 H 7 N 7 S, the essentially planar triazole ring and the 4-amino-5-mercapto-1,2,4-triazole moiety make a dihedral angle of 70.97 (5) . In the crystal structure, weak intermolecular N-Hร ร รN and N-Hร ร รS hydrogen bonds stabilize the packing.