Synthesis and antitumor activity of 4-[p-[bis(2-chloroethyl)amino]phenyl]butyrates
โ Scribed by Gerald R. Roehrig; John H. Billman; Jerome Marcec; Paul Fritz; Frank Shea
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 292 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The average of five replicate determinations for percent intact melphalan in a single vial of dosage formulation was 88.7% with a standard deviation of 1 (range = 2.5 %). Variations of less than 3 % were found in the assay of several vials from the same production lot. The samples and reference sol
In order to search for novel antitumor drugs with high activity and low toxicity, a series of new compounds, galactopyranosyl (or glucofuranosyl) N,N-bis(Z-chloroethyl) phosphoramidates, have been synthesized. The structures of all compounds prepared were proved by ' H NMR, 31P NMR, IR, and M S spec