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Synthesis and Antituberculous Activityin vitroof Amidine and Hydrazidine Analogs of Pyrazinamide and Isoniazid

✍ Scribed by R. G. Glushkov; G. A. Modnikova; A. I. L'vov; L. Yu. Krylova; T. V. Pushkina; T. A. Gus'kova; N. P. Solov'eva


Book ID
111603421
Publisher
Springer
Year
2004
Tongue
English
Weight
101 KB
Volume
38
Category
Article
ISSN
0091-150X

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Isoniazid and pyrazinamide are well-known hepatotoxic drugs, often used in combination. The aim of this study was to assess the prognostic influence of pyrazinamide on the outcome of fulminant or subfulminant liver failure caused by antituberculous therapy. Eighteen patients with fulminant or subful