## Abstract For Abstract see ChemInform Abstract in Full Text.
Synthesis and Antimycobacterial Activity of Some β -Carboline Alkaloids
✍ Scribed by Begum, Sabira; Hassan, Syed Imran; Siddiqui, Bina S.
- Book ID
- 125427232
- Publisher
- Taylor and Francis Group
- Year
- 2004
- Tongue
- English
- Weight
- 153 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1478-6419
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## Abstract The first total synthesis of the β‐carboline alkaloids arenarine A **(1)** and arenarine B **(2)** is described. Methanolysis of the α‐bromoketone **9** gives **1** in good yield. Alternatively **1** can be obtained from the diazoketone **11** with boron trifluoride/methanol in poor yie
## Abstract β‐Carbolines (**1–5**) undergo electrophilic aromatic substitution with __N__‐bromosuccinimide under different experimental conditions. Although 6‐bromo‐nor‐harmane (**la**) obtained by bromination of nor‐harmane (**1**) was isolated and fully characterized sometime ago, the other bromo