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Synthesis and antimycobacterial activity of isoniazid derivatives from renewable fatty acids

✍ Scribed by Rodrigues, Marieli O.; Cantos, Jéssica B.; D’Oca, Caroline R. Montes; Soares, Karina L.; Coelho, Tatiane S.; Piovesan, Luciana A.; Russowsky, Dennis; da Silva, Pedro A.; D’Oca, Marcelo G. Montes

Book ID
121240106
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
715 KB
Volume
21
Category
Article
ISSN
0968-0896

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## Abstract 4‐Substituted 1‐(__p__‐methoxybenzyl)imidazoles were designed and synthesized in order to mimic parts of the structure of highly potent antimycobacterial 6‐aryl‐9‐(__p__‐methoxybenzyl)purines. 4‐Haloimidazoles were subjected to Pd‐catalyzed cross‐coupling in order to introduce a (hetero